Electronic Library MSUPE : Perepelkina, Poletayeva and etc. [Modeling of human brain diseases in experiments on rodents (brief overview)]

Description

Perepelkina O. V., Poletayeva I. I., Tarasova A. Yu. Modelirovaniye zabolevaniy mozga cheloveka v eksperimentakh na gryzunakh (kratkiy obzor) = [Modeling of human brain diseases in experiments on rodents (brief overview)] // Sovremennaya zarubezhnaya psikhologiya. — 2016. — № 4. — S. 13—23. — URL: https://psychlib.ru/inc/absid.php?absid=406233.

Rubrics:

• General psychology → Experimental psychology

• Psychology of separate types of activity. Branch psychology → Other types of branch psychology

• Psychology of separate types of activity. Branch psychology → Medical psychology

• Scientific literature

Abstract:
The review summarizes the successes and difficulties in creating and using biological models of the human brain diseases, which belongs to the important issues of applied Neurobiology. The review mentions and attempts to theoretically comprehend the relative role of genotype, environmental influences and their dynamic interactions (LEARN concept). The article reviews the examples of developed genetic models of human diseases (Alzheimer’s, Down syndrome, Autism, etc.). When creating models of anxiety disorders the focus is made on the difficult problem of “norm” and “pathology”, as well as the importance of integrating and understanding species specific behavior of animals used as biological models of this kind.

• Open description in electronic catalog: 406233

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